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Artificial Regeneration 

NANO Direct cell reprogramming, also called direct conversion, is an efficient strategy that provides effective cell therapy because it allows the rapid generation of patient-specific target cells using autologous cells from the tissue biopsy. Fibroblasts are the cells that are commonly found within the connective tissues, and they are extensively involved in wound healing. As the fibroblasts are not terminally differentiated cells, it is possible to turn them into induced myogenic progenitor cells (iMPCs) using several different transcription factors. 


Tissue engineering

Tissue engineering is an emerging multidisciplinary scientific approach aiming to replace lost, damaged, or failing tissue and organs. Exploiting histology, stem cell biology, and chemical engineering knowledge; tissue engineering aims to generate innovative biomaterials, mimicking extracellular matrix (ECM) features (stiffness, elasticity, and adhesion) in order to support cell survival, growth, and differentiation, and to guarantee the scaffolding to reconstruct the complex tissue architecture. The regeneration of new muscle fibers through tissue engineering represents a powerful alternative for the replacement of skeletal muscle tissue after severe damage. 

View in microscopic of normal human cervix cells.Squamous epithelial cells..jpg
Biological texture. Element of design..jpg
Medical technologists are preparing pathological specimens for diagnosis..jpg
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